Improving reproductive performance in overweight-obese women with effective weight management

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dc.contributor.authorNorman, R.
dc.contributor.authorNoakes, M.
dc.contributor.authorWu, R.
dc.contributor.authorDavies, M.
dc.contributor.authorMoran, L.
dc.contributor.authorWang, J.
dc.date.issued2004
dc.description© European Society of Human Reproduction and Embryology 2004; all rights reserved
dc.description.abstractObesity and overweight are common conditions in the developed countries and they carry many health consequences, including some reproductive disorders. There is a very high prevalence of obese women in the infertile population and many studies have highlighted the link between obesity and infertility. A large proportion of infertile women have polycystic ovary syndrome (PCOS) which is also linked with increased risk of obesity and other metabolic anomalies. The association between obesity and/or PCOS and hyperinsulinaemia, hyper androgenism and abnormal secretion of other hormones, such as leptin, underlies many reproductive disorders observed in this population. It has been demonstrated that weight loss can improve the fertility of obese women through the recovery of spontaneous ovulation, whereas others will have improved response to ovarian stimulation in infertility treatment. Therefore, it is proposed that following the initial assessment of infertility and body mass index or other measurement of obesity, various weight management interventions, including diet, exercise or pharmacotherapeutic approaches, should be considered for overweight and obese infertile women.
dc.description.statementofresponsibilityRobert J. Norman, Manny Noakes, Ruijin Wu, Michael J. Davies, Lisa Moran and Jim X. Wang
dc.identifier.citationHuman Reproduction Update, 2004; 10(3):267-280
dc.identifier.doi10.1093/humupd/dmh018
dc.identifier.issn1355-4786
dc.identifier.issn1460-2369
dc.identifier.orcidNorman, R. [0000-0002-3118-3896]
dc.identifier.orcidDavies, M. [0000-0002-5809-7541] [0000-0003-1526-0801]
dc.identifier.orcidMoran, L. [0000-0001-5772-6484]
dc.identifier.urihttp://hdl.handle.net/2440/8235
dc.language.isoen
dc.publisherOxford Univ Press
dc.source.urihttps://doi.org/10.1093/humupd/dmh018
dc.subjectFertility
dc.subjectfitness
dc.subjectobese
dc.subjectoverweight
dc.subjectPCOS
dc.subjectweight loss
dc.titleImproving reproductive performance in overweight-obese women with effective weight management
dc.typeJournal article
pubs.publication-statusPublished

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