ATG8ylation of proteins: a way to cope with cell stress?
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(Published version)
Date
2021
Authors
Carosi, J.M.
Nguyen, T.N.
Lazarou, M.
Kumar, S.
Sargeant, T.J.
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Journal of Cell Biology, 2021; 220(11):1-4
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Julian M. Carosi, Thanh N. Nguyen, Michael Lazarou, Sharad Kumar and Timothy J. Sargeant
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Abstract
The ATG8 family of proteins regulates autophagy in a variety of ways. Recently, ATG8s were demonstrated to conjugate directly to cellular proteins in a process termed "ATG8ylation," which is amplified by mitochondrial damage and antagonized by ATG4 proteases. ATG8s may have an emerging role as small protein modifiers.
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© 2021 Carosi et al. This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).