Chromosomal localization of the human urothelial "tetraspan" gene, UPK1B, to 3q13.3-q21 and detection of aTaqI polymorphism
Date
1997
Authors
Finch, J.
Webb, G.
Evdokiou, A.
Cowled, P.
Editors
Advisors
Journal Title
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Volume Title
Type:
Journal article
Citation
Genomics, 1997; 40(3):501-503
Statement of Responsibility
Jennie L. Finch, Graham C. Webb, Andreas Evdokiou, Prudence A. Cowled
Conference Name
Abstract
The TI1/UPK1b gene codes for a protein of the “tetraspan” family and is expressed as a differentiation product of the mammalian urothelium. A partial genomic clone of the human homologue of the TI1/UPK1b gene was isolated and used as probe to localize the human gene to chromosome 3q13.3–q21 byin situhybridization. Using the same probe, aTaqI restriction fragment length polymorphism, with 29% heterozygosity, was identified by Southern analysis.