Expression of the homeobox gene Barx2 in the gut

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dc.contributor.authorSander, G.
dc.contributor.authorPowell, B.
dc.date.issued2004
dc.description© The Histochemical Society
dc.description.abstractBarx2 is a member of the Bar class of homeobox genes and has been shown to regulate specific cell adhesion molecules, L1, Ng-CAM, N-CAM, and cadherin 6. By Northern blotting and in situ hybridization, we show that Barx2 is expressed throughout the gut and is located in epithelial cells of the proliferative and differentiative regions of the stomach, esophagus, and intestine. Barx2 was expressed in muscle cells of the muscularis externa and also showed a graded pattern of expression in intestinal enterocytes, decreasing in a crypt-to-villous direction. We speculate that Barx2 may regulate cell adhesion molecules in epithelial cells of the gut.
dc.description.statementofresponsibilityGuy R. Sander and Barry C. Powell
dc.identifier.citationJournal of Histochemistry and Cytochemistry, 2004; 52(4):541-544
dc.identifier.doi10.1177/002215540405200412
dc.identifier.issn0022-1554
dc.identifier.issn1551-5044
dc.identifier.urihttp://hdl.handle.net/2440/7492
dc.language.isoen
dc.publisherHistochemical Soc Inc
dc.source.urihttps://doi.org/10.1177/002215540405200412
dc.subjectBarx
dc.subjecthomeobox
dc.subjectL1 cell adhesion molecule
dc.subjectcadherin
dc.titleExpression of the homeobox gene Barx2 in the gut
dc.typeJournal article
pubs.publication-statusPublished

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