Non-invasive evaluation of myocardial fibrosis: implications for the clinician

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2010

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Leong, D.
Madsen, P.
Selvanayagam, J.

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Heart, 2010; 96(24):2016-2024

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Darryl P. Leong, Per Lav Madsen, Joseph B. Selvanayagam

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The presence and extent of myocardial fibrosis are key determinants of response to treatment and prognosis in a number of cardiac conditions. Until recently, myocardial fibrosis could only be detected ante mortem by endomyocardial biopsy, which is associated with procedural risk and sampling error. The development of novel cardiac imaging techniques and serum assays now permits the accurate detection and quantification of myocardial fibrosis. These have yielded new insights into disease prognosis and response to treatment.

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