X-Y chromosome dissociation in mice and rats exposed to increased testicular or environmental temperatures

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dc.contributor.authorVan Zelst, S.
dc.contributor.authorZupp, J.
dc.contributor.authorHayman, D.
dc.contributor.authorSetchell, B.
dc.date.issued1995
dc.description.abstractHeating the testes, scrota and tails of mice and rats by immersion in a water bath at 42 degrees C for 20 min caused an increased percentage of X-Y univalents in meiotic preparations made after 6 and 12 days respectively. It was also confirmed that exposing mice of a cool-adapted strain to an environment at 33 degrees C for 5 days resulted in an increase in the percentage of X-Y and autosomal univalents in meiotic preparations made after a recovery period of 2 days. Mice of a strain adapted to living at 33 degrees C also showed a higher rate of X-Y dissociation than control cool-adapted mice, but a lower frequency of autosomal univalents than cool-adapted mice exposed to the hot environment. The testes of the heat-adapted mice were even more sensitive than the testes of cool-adapted mice to the effects of local heating, as judged by the fall in testis weight 21 days afterwards.
dc.description.statementofresponsibilityS. J. Van Zelst, J. L. Zupp, D. L. Hayman annd B. P. Setchell
dc.identifier.citationReproduction Fertility and Development, 1995; 7(5):1117-1121
dc.identifier.doi10.1071/RD9951117
dc.identifier.issn1031-3613
dc.identifier.issn1448-5990
dc.identifier.urihttp://hdl.handle.net/2440/11503
dc.language.isoen
dc.publisherCSIRO
dc.rights© CSIRO 1995
dc.source.urihttps://doi.org/10.1071/rd9951117
dc.subjectTestis
dc.subjectSpermatozoa
dc.subjectX Chromosome
dc.subjectY Chromosome
dc.subjectAnimals
dc.subjectMice
dc.subjectRats
dc.subjectRats, Wistar
dc.subjectSex Chromosome Aberrations
dc.subjectBody Temperature
dc.subjectMeiosis
dc.subjectMale
dc.subjectHot Temperature
dc.titleX-Y chromosome dissociation in mice and rats exposed to increased testicular or environmental temperatures
dc.typeJournal article
pubs.publication-statusPublished

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