The first practical approach to optically pure cyclopropanes derived from trans g-hydroxy enones
Date
2000
Authors
Palmer, F.
Taylor, D.
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Journal article
Citation
Organic and Biomolecular Chemistry, 2000; 1(9):1323-1325
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Abstract
The optically pure cyclopropanes derived from trans γ-hydroxy enones were discussed. The trans γ-hydroxy enones were found to be prepared from reaction of stabilized ketoylides on optically pure α hydroxy aldehydes. The analysis showed that the use of light and a triplet sensitizer lead to a dramatic increase in reaction rate and isolated yield.