Pathological evidence of encephalomyelitis in the stiff man syndrome with anti-GAD antibodies

Simple item page
dc.contributor.authorWarren, J.
dc.contributor.authorScott, G.
dc.contributor.authorBlumbergs, P.
dc.contributor.authorThompson, P.
dc.date.issued2002
dc.descriptionCopyright © 2002 Elsevier Science Ltd. All rights reserved.
dc.description.abstractWe report the case of a 57 year old woman with typical clinical features of the stiff man syndrome (SMS) and antibodies to glutamic acid decarboxylase (antiGADAb), who developed a supranuclear gaze palsy, ileus and died of bronchopneumonia eight years after the onset of illness. Post mortem examination revealed perivascular lymphocyte cuffing throughout the cerebral hemispheres, brainstem and spinal cord and neuronal loss in medial anterior horns of the cervical spinal cord. These findings support the notion that the SMS and progressive encephalomyelitis with rigidity (PER) form a clinical and pathologic continuum.
dc.description.statementofresponsibilityJason D. Warren, Grace Scott, Peter C. Blumbergs, and Philip D. Thompson
dc.identifier.citationJournal of Clinical Neuroscience, 2002; 9(3):328-329
dc.identifier.doi10.1054/jocn.2001.1014
dc.identifier.issn0967-5868
dc.identifier.issn1532-2653
dc.identifier.urihttp://hdl.handle.net/2440/38796
dc.language.isoen
dc.publisherChurchill Livingstone
dc.source.urihttps://doi.org/10.1054/jocn.2001.1014
dc.subjectCentral Nervous System
dc.subjectHumans
dc.subjectStiff-Person Syndrome
dc.subjectEncephalomyelitis
dc.subjectGlutamate Decarboxylase
dc.subjectAntibodies
dc.subjectFatal Outcome
dc.subjectMiddle Aged
dc.subjectFemale
dc.titlePathological evidence of encephalomyelitis in the stiff man syndrome with anti-GAD antibodies
dc.typeJournal article
pubs.publication-statusPublished

Files

Collections

Medicine publications