Pseudoexfoliation in a rural Burmese population: the Meiktila eye study

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dc.contributor.authorAbdul-Rahman, A.
dc.contributor.authorCasson, R.
dc.contributor.authorNewland, H.
dc.contributor.authorMuecke, J.
dc.contributor.authorMcGovern, S.
dc.contributor.authorAung, T.
dc.contributor.authorSelva-Nayagam, D.
dc.contributor.authorAung, T.
dc.date.issued2008
dc.description.abstract<h4>Aims</h4>The aim of this study was to report on the prevalence and correlates of pseudoexfoliation syndrome (PXF) in a rural Burmese population.<h4>Methods</h4>The study was a cross-sectional, population-based survey of the inhabitants > or =40 years in the Meiktila District. Ophthalmic examination included Snellen visual acuity, slit lamp examination, tonometry, gonioscopy, dilated fundus examination and frequency doubling perimetry.<h4>Results</h4>In a population of 2076 subjects (4016 eyes) the prevalence of PXF was 3.4% (95% CI 2.14 to 4.67%; 78 eyes). Twelve eyes with PXF were blind. In the univariate analysis, PXF was associated with: increasing age, blindness (odds ratio (OR) 4, 95% CI 1.84 to 8.68; p<0.0004), increasing intraocular pressure (IOP) (OR 1.08, 95% CI 1.04 to 1.11; p<0.00001), nuclear cataract (OR 6.92, 95% CI 2.89 to 16.59; p<0.00001), cortical cataract (OR 4.78, 95% CI 2.37 to 9.65; p<0.00001) and the presence of an occludable angle (OR 3.05, 95% CI 1.52 to 6.13; p<0.002). In the multivariate analysis, only increasing age and IOP remained significantly associated with PXF.<h4>Conclusions</h4>The prevalence of PXF in the Burmese population is greater than previously reported in other East Asian populations. Increasing age and IOP are the strongest predictors of PXF, and it is associated with cataract, occludable angles and blindness.
dc.description.statementofresponsibilityA. M. Abdul-Rahman, R. J. Casson, H. S. Newland, J. Muecke, S. McGovern, T. H. Aung, D. Selva, T. Aung
dc.identifier.citationBritish Journal of Ophthalmology, 2008; 92(10):1325-1328
dc.identifier.doi10.1136/bjo.2008.141523
dc.identifier.issn0007-1161
dc.identifier.issn1468-2079
dc.identifier.orcidCasson, R. [0000-0003-2822-4076]
dc.identifier.orcidSelva-Nayagam, D. [0000-0002-2169-5417]
dc.identifier.urihttp://hdl.handle.net/2440/53718
dc.language.isoen
dc.publisherBritish Med Journal Publ Group
dc.source.urihttps://doi.org/10.1136/bjo.2008.141523
dc.subjectHumans
dc.subjectBlindness
dc.subjectCataract
dc.subjectGlaucoma
dc.subjectExfoliation Syndrome
dc.subjectTonometry, Ocular
dc.subjectRisk Factors
dc.subjectCross-Sectional Studies
dc.subjectPredictive Value of Tests
dc.subjectAge Distribution
dc.subjectIntraocular Pressure
dc.subjectAdult
dc.subjectAged
dc.subjectMiddle Aged
dc.subjectRural Health
dc.subjectMyanmar
dc.subjectFemale
dc.subjectMale
dc.titlePseudoexfoliation in a rural Burmese population: the Meiktila eye study
dc.typeJournal article
pubs.publication-statusPublished

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