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Late presentation of upper airway obstruction in Pierre Robin sequence

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dc.contributor.authorWilson, A.
dc.contributor.authorMoore, D.
dc.contributor.authorMoore, M.
dc.contributor.authorMartin, A.
dc.contributor.authorStaugas, R.
dc.contributor.authorKennedy, J.
dc.date.issued2000
dc.descriptionCopyright © 2000 by the BMJ Publishing Group Ltd.
dc.description.abstractA retrospective review was carried out of 11 consecutive patients with the Pierre Robin sequence referred to a tertiary paediatric referral centre over a five year period from 1993 to 1998. Ten patients were diagnosed with significant upper airway obstruction; seven of these presented late at between 24 and 51 days of age. Failure to thrive occured in six of these seven infants at the time of presentation, and was a strong indicator of the severity of upper airway obstruction. Growth normalised on treatment of the upper airway obstruction with nasopharyngeal tube placement. All children had been reviewed by either an experienced general paediatrician or a neonatologist in the first week of life, suggesting that clinical signs alone are insufficent to alert the physician to the degree of upper airway obstruction or that obstruction developed gradually after discharge home. The use of polysomnography greatly improved the diagnostic accuracy in assesssing the severity of upper airway obstruction and monitoring the response to treatment. This report highlights the prevalence of late presentation of upper airway obstruction in the Pierre Robin sequence and emphasises the need for close prospective respiratory monitoring in this condition. Objective measures such as polysomnography should be used, as clinical signs alone may be an inadequate guide to the degree of upper airway obstruction.
dc.description.statementofresponsibilityA C Wilson, D J Moore, M H Moore, A J Martin, R E M Staugas, J D Kennedy
dc.identifier.citationArchives of Disease in Childhood, 2000; 83(5):435-438
dc.identifier.doi10.1136/adc.83.5.435
dc.identifier.issn0003-9888
dc.identifier.issn1468-2044
dc.identifier.orcidMoore, M. [0000-0003-2136-0315]
dc.identifier.orcidMartin, A. [0000-0002-1606-5461]
dc.identifier.orcidKennedy, J. [0000-0003-2308-1870]
dc.identifier.urihttp://hdl.handle.net/2440/6970
dc.language.isoen
dc.publisherBritish Med Journal Publ Group
dc.source.urihttps://doi.org/10.1136/adc.83.5.435
dc.subjectHumans
dc.subjectPierre Robin Syndrome
dc.subjectAirway Obstruction
dc.subjectFailure to Thrive
dc.subjectPolysomnography
dc.subjectRetrospective Studies
dc.subjectAge of Onset
dc.subjectInfant
dc.subjectInfant, Newborn
dc.subjectInfant, Premature
dc.subjectFemale
dc.subjectMale
dc.titleLate presentation of upper airway obstruction in Pierre Robin sequence
dc.typeJournal article
pubs.publication-statusPublished

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