Factors influencing the development of wound infection following free-flap reconstruction for intra-oral cancer
| dc.contributor.author | Cloke, D. | |
| dc.contributor.author | Green, J. | |
| dc.contributor.author | Khan, A. | |
| dc.contributor.author | Hodgkinson, P. | |
| dc.contributor.author | McLean, N. | |
| dc.date.issued | 2004 | |
| dc.description.abstract | Wound infection following tissue transfer in head and neck oncology is common. Factors known to be associated with infective complications include blood transfusion, pre-operative radiotherapy, duration of surgery, duration of pre-operative stay and a history of smoking. The present study specifically examined 100 consecutive patients on a standard antibiotic protocol undergoing free flap reconstruction following resection of cancers of the oral cavity or oropharynx. Despite prophylactic antibiotics, 21 patients developed a head and neck wound infection. No statistically significant association was found between infective wound complications and a history of smoking, pre-operative radiotherapy or chemotherapy, length of pre-operative hospital stay, duration of surgery, or number of units of blood transfused. We conclude that, in this group of patients, wound infection is a common and difficult problem, but with no statistically significant association with any of the variables studied. | |
| dc.identifier.citation | Journal of Plastic, Reconstructive and Aesthetic Surgery, 2004; 57(7):556-560 | |
| dc.identifier.doi | 10.1016/j.bjps.2004.04.006 | |
| dc.identifier.issn | 1748-6815 | |
| dc.identifier.issn | 0007-1226 | |
| dc.identifier.uri | http://hdl.handle.net/2440/10549 | |
| dc.language.iso | en | |
| dc.publisher | Print Edition - Churchill Livingstone | |
| dc.source.uri | https://doi.org/10.1016/j.bjps.2004.04.006 | |
| dc.subject | Surgical Flaps | |
| dc.subject | Humans | |
| dc.subject | Staphylococcal Infections | |
| dc.subject | Surgical Wound Infection | |
| dc.subject | Mouth Neoplasms | |
| dc.subject | Cefuroxime | |
| dc.subject | Metronidazole | |
| dc.subject | Drug Therapy, Combination | |
| dc.subject | Premedication | |
| dc.subject | Prospective Studies | |
| dc.subject | Adult | |
| dc.subject | Aged | |
| dc.subject | Aged, 80 and over | |
| dc.subject | Middle Aged | |
| dc.subject | Female | |
| dc.subject | Male | |
| dc.subject | Plastic Surgery Procedures | |
| dc.title | Factors influencing the development of wound infection following free-flap reconstruction for intra-oral cancer | |
| dc.type | Journal article | |
| pubs.publication-status | Published |