Human variation in response to food and nutrients

dc.contributor.authorHead, R.J.
dc.contributor.authorBuckley, J.D.
dc.contributor.conference8th International Conference on Nutrition and Aging (1 Oct 2019 - 2 Oct 2019 : Tokyo, Japan)
dc.date.issued2020
dc.description.abstractThe application of science to human nutrition over the centuries has served societies well. One example is the identification of key nutrients to overcome nutritional deficiencies, which has enhanced life expectancy. Enhanced life expectancy, however, is associated with an increased prevalence of chronic disorders related to food and nutrition. Findings of studies indicating that individual responses to nutrients differ substantially between individuals make it necessary to re-examine the relationship between nutrition and human health. The emergence of new genomic-based technologies illustrates the complexity and scale of the interactions between nutrition and genetic factors. Epigenetic modifications resulting from interactions of the genetic profile, aging, and lifestyle can influence the time course of chronic disorders and contribute to human variability in response to nutritional interventions. Developing a better understanding of human variability as it applies to human nutrition will involve embracing the approaches and principles of complex science.
dc.identifier.citationNutrition Reviews, 2020, vol.78, iss.S3, pp.49-52
dc.identifier.doi10.1093/nutrit/nuaa068
dc.identifier.issn0029-6643
dc.identifier.issn1753-4887
dc.identifier.orcidHead, R.J. [0000-0002-1196-0926]
dc.identifier.orcidBuckley, J.D. [0000-0003-0298-2186]
dc.identifier.urihttps://hdl.handle.net/11541.2/146225
dc.language.isoen
dc.publisherOxford University Press
dc.publisher.placeUS
dc.rightsCopyright 2020 The Authors
dc.source.urihttps://doi.org/10.1093/nutrit/nuaa068
dc.subjectchronic diseases
dc.subjectcomplex science
dc.subjectepigenetics
dc.subjectgenome
dc.subjecthuman variability
dc.subjectlongevity
dc.subjectnutrition
dc.subjectpersonalized nutrition
dc.titleHuman variation in response to food and nutrients
dc.typeConference paper
pubs.publication-statusPublished
ror.mmsid9916484107301831

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