Nutrition therapy for diabetic gastroparesis

Date

2003

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Gentilcore, D.
O'Donovan, D.
Jones, K.
Horowitz, M.

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Journal article

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Current Diabetes Reports, 2003; 3(5):418-426

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Diana Gentilcore, Deirdre O’Donovan, Karen L. Jones, and Michael Horowitz

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Abstract

The management of diabetic gastroparesis often represents a significant clinical challenge in which the maintenance of nutrition is pivotal. Gastric emptying is delayed in 30% to 50% of patients with longstanding type 1 or type 2 diabetes and upper gastrointestinal symptoms also occur frequently. However, there is only a weak association between the presence of symptoms and delayed gastric emptying. Acute changes in blood glucose concentrations affect gastric motility in diabetes; hyperglycemia slows gastric emptying whereas hypoglycemia may accelerate it; blood glucose concentrations may also influence symptoms. It is now recognized that gastric emptying is a major determinant of postprandial glycemia and, therefore, there is considerable interest in the concept of modulating gastric emptying, by dietary or pharmacologic means, to optimize glycemic control in diabetes.

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The original publication is available at www.springerlink.com Copyright © 2003 by Current Science Inc.

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