Safe use of statins in elderly people
Date
2014
Authors
Westaway, K.
Frank, O.
Husband, A.
Rowet, D.
Rossi, S.
Blanc, T.
Shute, R.
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Journal article
Citation
Journal of Pharmacy Practice and Research, 2014; 44(3):138-142
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Abstract
Multiple medicine use is common in older Australians, with statins (hydroxymethylglutaryl coenzyme A reductase inhibitors) being among the most commonly prescribed. While there is significant evidence that statins are of benefit in people at higher levels of cardiovascular risk, the risk-benefit ratio is less assured in those 80 years and older. Flight doses or high-potency statins in elderly people may not increase effectiveness, but may increase the risk of ad verse effects such as muscle-related aches, pains and weakness. Hence, statin use in the elderly requires frequent review and consideration of their therapeutic goals, quality of life, risk-benefit ratio and life expectancy. This paper outlines steps to consider when an older person who is prescribed a statin experiences unexplained muscle-related aches and pains or weakness.
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Link to a related website: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jppr.1022, Open Access via Unpaywall
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Copyright 20l4 Society of Hospital Pharmacists of Australia.