Automatic localization of the left ventricular blood pool centroid in short axis cardiac cine MR images

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dc.contributor.authorTan, L.
dc.contributor.authorLiew, Y.
dc.contributor.authorLim, E.
dc.contributor.authorAbdul Aziz, Y.
dc.contributor.authorChee, K.
dc.contributor.authorMcLaughlin, R.
dc.date.issued2018
dc.description.abstractIn this paper, we develop and validate an open source, fully automatic algorithm to localize the left ventricular (LV) blood pool centroid in short axis cardiac cine MR images, enabling follow-on automated LV segmentation algorithms. The algorithm comprises four steps: (i) quantify motion to determine an initial region of interest surrounding the heart, (ii) identify potential 2D objects of interest using an intensity-based segmentation, (iii) assess contraction/expansion, circularity, and proximity to lung tissue to score all objects of interest in terms of their likelihood of constituting part of the LV, and (iv) aggregate the objects into connected groups and construct the final LV blood pool volume and centroid. This algorithm was tested against 1140 datasets from the Kaggle Second Annual Data Science Bowl, as well as 45 datasets from the STACOM 2009 Cardiac MR Left Ventricle Segmentation Challenge. Correct LV localization was confirmed in 97.3% of the datasets. The mean absolute error between the gold standard and localization centroids was 2.8 to 4.7 mm, or 12 to 22% of the average endocardial radius.
dc.description.statementofresponsibilityLi Kuo Tan, Yih Miin Liew, Einly Lim, Yang Faridah Abdul Aziz, Kok Han Chee and Robert A McLaughlin
dc.identifier.citationMedical and Biological Engineering and Computing, 2018; 56(6):1053-1062
dc.identifier.doi10.1007/s11517-017-1750-7
dc.identifier.issn0140-0118
dc.identifier.issn1741-0444
dc.identifier.orcidMcLaughlin, R. [0000-0001-6947-5061]
dc.identifier.urihttp://hdl.handle.net/2440/109965
dc.language.isoen
dc.publisherSpringer
dc.relation.granthttp://purl.org/au-research/grants/arc/CE140100003
dc.relation.granthttp://purl.org/au-research/grants/arc/DP150104660
dc.rights© International Federation for Medical and Biological Engineering 2017
dc.source.urihttps://doi.org/10.1007/s11517-017-1750-7
dc.subjectCardiovascular MRI; automatic localization; segmentation; left ventricle; cine MRI
dc.titleAutomatic localization of the left ventricular blood pool centroid in short axis cardiac cine MR images
dc.typeJournal article
pubs.publication-statusPublished

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