Behaviour and gastroesophageal reflux in the premature neonate

Simple item page
dc.contributor.authorSnel, A.
dc.contributor.authorBarnett, C.
dc.contributor.authorCresp, T.
dc.contributor.authorHaslam, R.
dc.contributor.authorDavidson, G.
dc.contributor.authorMalbert, C.
dc.contributor.authorDent, J.
dc.contributor.authorOmari, T.
dc.date.issued2000
dc.description.abstract<h4>Background</h4>The belief that behavioral observations assist in the clinical diagnosis of gastroesophageal reflux (GER) disease in premature neonates has not been formally tested. The purpose of this study was to determine whether esophageal acidification was associated with a recognizable pattern of behavioral changes in these infants.<h4>Methods</h4>The behavior of 14 healthy premature infants was recorded by a video camera while esophageal pH was simultaneously monitored. For each of 20 acid GER episodes recorded, a 10-minute video epoch, encompassing the onset of acid GER and lasting at least 4 minutes after the onset of GER, was examined. Two independent observers each scored reflux-associated epochs of "general" infant behavior and behavior previously shown to be indicative of reflux in normal term infants.<h4>Results</h4>The occurrence of esophageal acidification due to reflux did not significantly alter scores for general behavior. Infants frequently demonstrated reflux-specific behavior, including discomfort, head retraction, and mouthing; however, none of these behavioral patterns was temporally associated with the occurrence of acid GER.<h4>Conclusions</h4>These data indicate that reflux-specific behavioral criteria, established in older term infants, may be inappropriate as diagnostic criteria for GER in premature neonates and may lead to the unnecessary use of antireflux therapy.
dc.identifier.citationJournal of Pediatric Gastroenterology and Nutrition, 2000; 30(1):18-21
dc.identifier.doi10.1097/00005176-200001000-00012
dc.identifier.issn0277-2116
dc.identifier.issn1536-4801
dc.identifier.orcidBarnett, C. [0000-0003-1717-3824]
dc.identifier.orcidMalbert, C. [0000-0002-0665-4545]
dc.identifier.orcidOmari, T. [0000-0001-5108-7378]
dc.identifier.urihttp://hdl.handle.net/2440/9640
dc.language.isoen
dc.publisherLippincott Williams & Wilkins
dc.source.urihttps://doi.org/10.1097/00005176-200001000-00012
dc.subjectHumans
dc.subjectGastroesophageal Reflux
dc.subjectPain
dc.subjectInfant, Premature, Diseases
dc.subjectBehavior
dc.subjectCrying
dc.subjectHydrogen-Ion Concentration
dc.subjectInfant
dc.subjectInfant, Newborn
dc.subjectFemale
dc.subjectMale
dc.titleBehaviour and gastroesophageal reflux in the premature neonate
dc.typeJournal article
pubs.publication-statusPublished

Files

Collections

Medicine publications