Laparoscopic repair of perforated peptic ulcers. The role of laparoscopy in generalised peritonitis

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dc.contributor.authorRobertson, G.
dc.contributor.authorWemyss-Holden, S.
dc.contributor.authorMaddern, G.
dc.date.issued2000
dc.description.abstractThis non-randomised concurrent cohort study conducted in two teaching hospital Departments of Surgery examined the assumption that the benefits of elective laparoscopic upper gastrointestinal surgery would apply to those with generalised peritonitis due to perforated peptic ulcers. It compared 20 consecutive laparoscopic repairs of perforated peptic ulcers with a concurrent group of 16 consecutive open repairs. There were no differences pre-operatively between the two groups. The mean duration of surgery was similar (P = 0.46). There were no differences in the rate of GI tract recovery, but opiate analgesia requirement in the laparoscopic group was significantly less (P < 0.0001). Intensive care was required in three patients in the laparoscopic group (two with renal failure) and two in the open (no renal failure). Two patients in the laparoscopic and one in the open group died. The median duration of stay was five days in the laparoscopic group and six in the open. This comparison shows that the patho-physiological insult of laparoscopy in the setting of generalised peritonitis does not obviously increase the peri-operative risk of organ failure but objective benefits are small.
dc.identifier.citationAnnals of the Royal College of Surgeons of England, 2000; 82(1):6-10
dc.identifier.issn0035-8843
dc.identifier.issn1478-7083
dc.identifier.orcidMaddern, G. [0000-0003-2064-181X]
dc.identifier.urihttp://hdl.handle.net/2440/10274
dc.language.isoen
dc.publisherRoyal Coll Surgeons England
dc.subjectHumans
dc.subjectDuodenal Ulcer
dc.subjectPeptic Ulcer Perforation
dc.subjectPeritonitis
dc.subjectAnalgesics, Opioid
dc.subjectLaparoscopy
dc.subjectCritical Care
dc.subjectIntraoperative Period
dc.subjectDrug Administration Schedule
dc.subjectHospital Mortality
dc.subjectAdolescent
dc.subjectAdult
dc.subjectAged
dc.subjectAged, 80 and over
dc.subjectMiddle Aged
dc.subjectFemale
dc.subjectMale
dc.titleLaparoscopic repair of perforated peptic ulcers. The role of laparoscopy in generalised peritonitis
dc.typeJournal article
pubs.publication-statusPublished

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