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Subcutaneous fentanyl for labour analgesia: a retrospective case note review

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dc.contributor.authorFleet, J.
dc.contributor.authorSok, C.
dc.contributor.authorRandall, E.R.
dc.contributor.authorCyna, A.M.
dc.date.issued2021
dc.description.abstractBackground: In 2017, a South Australia Perinatal Practice Guideline was introduced state-wide for the use of subcutaneous fentanyl for labour analgesia as a replacement for intramuscular pethidine. We retrospectively reviewed the implementation of this practice change in our institution. Methods: A retrospective review of maternal and neonatal case notes for the first 100 women administered subcutaneous fentanyl in labour at a single tertiary referral centre for maternity care, between February and June 2017. Results: Of the 102 women administered subcutaneous fentanyl, the majority (55%) were primipara, with an average maternal age of 29 years and body mass index of 27 kg/m2. The median total fentanyl dose administered was 200 µg and the average time from last dose to birth was 3 h. The majority of women (70%) did not require additional rescue labour analgesia and 80% had a spontaneous vaginal birth. All neonates had a 5-min Apgar score >7. The median Apgar score at 1 and 5 min was 9. No neonate had an arterial cord blood pH <7.1. The mean arterial and venous cord blood pH was 7.3. The average time for neonates to establish breathing was 1 min and the median postnatal length of stay was two days. Conclusions: Subcutaneous fentanyl for labour analgesia appears effective and has a low incidence of adverse events.
dc.identifier.citationInternational Journal of Obstetric Anesthesia, 2021; 45:138-141
dc.identifier.doi10.1016/j.ijoa.2020.10.009
dc.identifier.issn0959-289X
dc.identifier.issn1532-3374
dc.identifier.orcidFleet, J. [0000-0001-6228-5636]
dc.identifier.orcidCyna, A.M. [0000-0002-3138-1091]
dc.identifier.urihttps://hdl.handle.net/11541.2/145456
dc.language.isoen
dc.publisherElsevier
dc.rightsCopyright 2020 Elsevier Access Condition Notes: Accepted manuscript available after 1 October 2022
dc.source.urihttps://doi.org/10.1016/j.ijoa.2020.10.009
dc.subjectfentanyl
dc.subjectlabour analgesia
dc.subjectsubcutaneous
dc.titleSubcutaneous fentanyl for labour analgesia: a retrospective case note review
dc.typeJournal article
pubs.publication-statusPublished
ror.fileinfo12245399050001831 13245399040001831 Open Access Postprint
ror.mmsid9916460797701831

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