Synchrotron X-ray fluorescence studies of a bromine-labelled cyclic RGD peptide interacting with individual tumor cells

Date

2013

Authors

Sheridan, E.
Austin, C.
Aitken, J.
Vogt, S.
Jolliffe, K.
Harris, H.
Rendina, L.

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Journal article

Citation

Journal of Synchrotron Radiation, 2013; 20(2):226-233

Statement of Responsibility

Erin J. Sheridan, Christopher J. D. Austin, Jade B. Aitken, Stefan Vogt, Katrina A. Jolliffe, Hugh H. Harris and Louis M. Rendina

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Abstract

The first example of synchrotron X-ray fluorescence imaging of cultured mammalian cells in cyclic peptide research is reported. The study reports the first quantitative analysis of the incorporation of a bromine-labelled cyclic RGD peptide and its effects on the biodistribution of endogenous elements (for example, K and Cl) within individual tumor cells.

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© 2013 International Union of Crystallography

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