Time to abandon dogma: CD14 is expressed by non-myeloid lineage cells

Simple item page
dc.contributor.authorJersmann, H.
dc.date.issued2005
dc.description© 2007 Australasian Society for Immunology
dc.description.abstractCD14 is a pattern recognition receptor; its important role in innate immunity is reviewed here. Since its discovery and subsequent classification at the first leucocyte typing workshop in 1982, CD14 has been thought of as a leucocyte differentiation antigen. However, it has become clear that CD14 is also expressed by many non-myeloid cells, and the evidence for this is presented. The possible role of the presence of low copy number CD14 on non-myeloid cells is discussed. It is time to acknowledge CD14 as an ubiquitous molecule and abandon the position that it is expressed by myeloid cells alone.
dc.identifier.citationImmunology and Cell Biology, 2005; 83(5):462-467
dc.identifier.doi10.1111/j.1440-1711.2005.01370.x
dc.identifier.issn0818-9641
dc.identifier.issn1440-1711
dc.identifier.orcidJersmann, H. [0000-0003-1763-2736]
dc.identifier.urihttp://hdl.handle.net/2440/17475
dc.language.isoen
dc.publisherBlackwell Publishing Asia
dc.source.urihttps://doi.org/10.1111/j.1440-1711.2005.01370.x
dc.subjectCD14
dc.subjectendothelial cell
dc.subjectepithelial cell
dc.subjectinnate immunity
dc.subjectLPS
dc.titleTime to abandon dogma: CD14 is expressed by non-myeloid lineage cells
dc.typeJournal article
pubs.publication-statusPublished

Files

Collections

Medicine publications