West Nile virus: the current climate

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2009

Authors

Prow, N.A.
Khromykh, A.A.
Hall, R.A.

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Journal article

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MLO: medical laboratory observer, 2009; 41(4):10-15

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Abstract

West Nile virus (WNV) is a member of the Japanese encephalitis antigenic complex of flaviviruses, which are responsible for a range of clinical syndromes in humans, from mild fever to fatal encephalitis. WNV is transmitted by many different mosquito species including Aedes, Culex, and Anopheles. The virus is maintained innature via a mosquito-bird-mosquito cycle, where humans and other animals are incidental hosts. Since the first detection of WNV in the Western Hemisphere in 1999, the virus has spread rapidly across North America and as far south as Argentina.1 This review focuses on recent outbreaks of WNV in the Americas and other parts of the world, as well as the latest advances in diagnostics, vaccines, and antiviral therapies.

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Copyright 2009 Nelson Publishing

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