International Consensus (ICON): allergic reactions to vaccines

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dc.contributor.authorDreskin, S.
dc.contributor.authorHalsey, N.
dc.contributor.authorKelso, J.
dc.contributor.authorWood, R.
dc.contributor.authorHummell, D.
dc.contributor.authorEdwards, K.
dc.contributor.authorCaubet, J.
dc.contributor.authorEngler, R.
dc.contributor.authorGold, M.
dc.contributor.authorPonvert, C.
dc.contributor.authorDemoly, P.
dc.contributor.authorSanchez-Borges, M.
dc.contributor.authorMuraro, A.
dc.contributor.authorLi, J.
dc.contributor.authorRottem, M.
dc.contributor.authorRosenwasser, L.
dc.date.issued2016
dc.description.abstractBackground: Routine immunization, one of the most effective public health interventions, has effectively reduced death and morbidity due to a variety of infectious diseases. However, allergic reactions to vaccines occur very rarely and can be life threatening. Given the large numbers of vaccines administered worldwide, there is a need for an international consensus regarding the evaluation and management of allergic reactions to vaccines. Methods: Following a review of the literature, and with the active participation of representatives from the World Allergy Organization (WAO), the European Academy of Allergy and Clinical Immunology (EAACI), the American Academy of Allergy, Asthma, and Immunology (AAAAI), and the American College of Allergy, Asthma, and Immunology (ACAAI), the final committee was formed with the purpose of having members who represented a wide-range of countries, had previously worked on vaccine safety, and included both allergist/immunologists as well as vaccinologists. Results: Consensus was reached on a variety of topics, including: definition of immediate allergic reactions, including anaphylaxis, approaches to distinguish association from causality, approaches to patients with a history of an allergic reaction to a previous vaccine, and approaches to patients with a history of an allergic reaction to components of vaccines. Conclusions: This document provides comprehensive and internationally accepted guidelines and access to on-line documents to help practitioners around the world identify allergic reactions following immunization. It also provides a framework for the evaluation and further management of patients who present either following an allergic reaction to a vaccine or with a history of allergy to a component of vaccines.
dc.description.statementofresponsibilityStephen C. Dreskin, Neal A. Halsey, John M. Kelso, Robert A. Wood, Donna S. Hummell ... Michael S. Gold ... et al.
dc.identifier.citationWorld Allergy Organization Journal, 2016; 9(1):32-32
dc.identifier.doi10.1186/s40413-016-0120-5
dc.identifier.issn1939-4551
dc.identifier.issn1939-4551
dc.identifier.orcidGold, M. [0000-0003-1312-5331]
dc.identifier.urihttp://hdl.handle.net/2440/115977
dc.language.isoen
dc.publisherBMC
dc.rights© 2016 Dreskin et al. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
dc.source.urihttps://doi.org/10.1186/s40413-016-0120-5
dc.subjectAllergic reactions
dc.subjectAllergy
dc.subjectAnaphylaxis
dc.subjectCausality
dc.subjectComponents
dc.subjectConsensus
dc.subjectInternational
dc.subjectVaccine
dc.titleInternational Consensus (ICON): allergic reactions to vaccines
dc.typeJournal article
pubs.publication-statusPublished

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