Prevalence of and risk factors for primary open-angle glaucoma in central Sri Lanka: The Kandy eye study

dc.contributor.authorSia, I.
dc.contributor.authorEdussuriya, K.
dc.contributor.authorSennanayake, S.
dc.contributor.authorSenaratne, T.
dc.contributor.authorSelva-Nayagam, D.
dc.contributor.authorCasson, R.
dc.date.issued2010
dc.description.abstractPurpose: To report the prevalence and risk factors associated with primary open-angle glaucoma (POAG) in the Kandy district of central Sri Lanka. Methods: A cross-sectional, population-based ophthalmic survey of the inhabitants ≥ 40 years of age from villages in the Kandy District, Sri Lanka was conducted. Selection was randomized using a cluster sampling process; 1721 eligible participants were identified, 1375 participated in the study and sufficient examination data to diagnose glaucoma in at least one eye was obtained in 1244 participants. A detailed ophthalmic history and examination including ocular biometry was made of each participant. Primary open-angle glaucoma was classified into three levels according to diagnostic evidence. Results: The overall prevalence of POAG was 2.3% (95% CI 1.5–3.2). In the univariate analyses, increasing age (P=0.001), intraocular pressure (IOP) (P<0.001), myopia (P<0.001) and axial length (P=0.003) were significantly associated with POAG. In the multivariate analysis, age (P=0.001), mean IOP (P<0.001) and mean axial length (P=0.008) were significant risk factors of POAG. Conclusions: The prevalence of POAG in the population aged ≥40 years in central Sri Lanka was 2.3%. POAG in this population was independently associated with increasing age, IOP and axial length.
dc.description.statementofresponsibilityDavid I.T. Sia, Kapila Edussuriya, Saman Sennanayake, Tissa Senaratne, Dinesh Selva and Robert J. Casson
dc.identifier.citationOphthalmic Epidemiology, 2010; 17(4):211-216
dc.identifier.doi10.3109/09286586.2010.483753
dc.identifier.issn0928-6586
dc.identifier.issn1744-5086
dc.identifier.orcidSia, I. [0000-0003-0749-7614]
dc.identifier.orcidSelva-Nayagam, D. [0000-0002-2169-5417]
dc.identifier.orcidCasson, R. [0000-0003-2822-4076]
dc.identifier.urihttp://hdl.handle.net/2440/61296
dc.language.isoen
dc.publisherInforma Healthcare
dc.rightsCopyright © 2010 Informa Plc. All rights reserved.
dc.source.urihttps://doi.org/10.3109/09286586.2010.483753
dc.subjectAxial length
dc.subjectEpidemiology
dc.subjectOpen-angle glaucoma
dc.subjectPrevalence
dc.subjectRisk factors
dc.subjectSri Lanka
dc.titlePrevalence of and risk factors for primary open-angle glaucoma in central Sri Lanka: The Kandy eye study
dc.typeJournal article
pubs.publication-statusPublished

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