Carbohydrate and satiety

dc.contributor.authorFeinle-Bisset, C.
dc.contributor.authorO'Donovan, D.
dc.contributor.authorHorowitz, M.
dc.date.issued2002
dc.description© 2002 International Life Sciences Institute
dc.description.abstractThis review focuses on what is known about the effects of carbohydrate on food intake, the potential mechanisms mediating these effects, and the impact of different monosaccharides in humans. The inhibition of subsequent food intake associated with ingestion of carbohydrate appears to result primarily from gastrointestinal signals, including those generated by orosensory stimulation, gastric distension, and perhaps most importantly the interaction of nutrients with receptors in the small intestine. The latter is associated with the release of putative satiety hormones, including glucagon-like peptide-1 and amylin, and slowing of both gastric emptying and small intestinal transit (thereby prolonging gastric distension and increasing the time available for nutrient absorption). The effects of carbohydrate on food intake are dependent on the route of administration (i.e., oral, intragastric, or intraduodenal). Changes in blood glucose and insulin concentrations per se probably do not play a major role in the induction of satiety. Studies relating to the comparative effects of different monosaccharides/carbohydrates have yielded inconclusive results, probably in part owing to substantial differences in methodological approaches.
dc.description.statementofresponsibilityChristine Feinle, Deirdre O’Donovan, and Michael Horowitz
dc.identifier.citationNutrition Reviews, 2002; 60(6):155-169
dc.identifier.doi10.1301/002966402320243241
dc.identifier.issn0029-6643
dc.identifier.issn1753-4887
dc.identifier.orcidFeinle-Bisset, C. [0000-0001-6848-0125]
dc.identifier.orcidHorowitz, M. [0000-0002-0942-0306]
dc.identifier.urihttp://hdl.handle.net/2440/9728
dc.language.isoen
dc.publisherInt Life Sciences Inst
dc.source.urihttps://doi.org/10.1301/002966402320243241
dc.subjectAnimals
dc.subjectPapio
dc.subjectHumans
dc.subjectRats
dc.subjectDietary Carbohydrates
dc.subjectMonosaccharides
dc.subjectSatiety Response
dc.subjectEating
dc.subjectFemale
dc.subjectMale
dc.subjectDigestive System Physiological Phenomena
dc.titleCarbohydrate and satiety
dc.typeJournal article
pubs.publication-statusPublished

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