Examining the role of melanin in disease states through its adsorption characteristics and their mechanisms /
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(Published version)
Date
2015
Authors
Schroeder, Rhiannon Lee,
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Type:
thesis
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Abstract
Melanin is a catecholamine-derived pigment found in a variety of biological systems. In humans its functions include photoprotection from Ultra Violet radiation, sound dampening, prevention of light scattering, and free radical scavenging. However, the pigment has been linked to a range of pathologies in association with drug binding and has consequently attracted much attention. In particular, this phenomenon has been associated with melanin located in the eyes and brain. Despite these being different types of melanin, they appear to have similar basic adsorptive propensities. This thesis examines the interactions between melanin and compounds related to disease to gain a greater insight into the chemistry of melanin, and to determine how it may play a role in disease.
School/Discipline
University of South Australia. School of Pharmacy and Medical Sciences.
School of Pharmacy and Medical Sciences.
School of Pharmacy and Medical Sciences.
Dissertation Note
Thesis (PhD)--University of South Australia, 2015.
Provenance
Copyright 2015 Rhiannon Lee Schroeder.
Description
1 ethesis (210 pages) :
illustrations (some colour).
Includes bibliographical references (leaves 123-149)
illustrations (some colour).
Includes bibliographical references (leaves 123-149)
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506 0#$fstar $2Unrestricted online access