Calcitonin
Date
2004
Authors
Findlay, D.
Sexton, P.
Editors
Advisors
Journal Title
Journal ISSN
Volume Title
Type:
Journal article
Citation
Growth Factors, 2004; 22(4):217-224
Statement of Responsibility
David M. Findlay and Patrick M. Sexton
Conference Name
Abstract
There is yet much to learn about the actions and role of CT. It will be important to better understand die physicochemistry of CT-CTR interaction, and the pharmacokinetics of CT, so that small molecule CT-mimetics and more potent, differently delivered, longer acting forms of the molecule can be designed to control bone resorption and turnover. It is important to understand the actions of CT in inflammation and stress, in the CNS, in blastocyst implantation and development, in cancer and in cell growth and morphogenesis, which could well have interesting and unexpected consequences. The recent recognition that the CTR can also interact with other peptides by collaborating with RAMPs, provides additional complexity to CT physiology. The study of CT in, as well as beyond its role as a calcium-regulating and bone-sparing hormone, will continue to provide insights of biological interest and of importance in our understanding of health and disease. © 2004 Taylor & Francis Ltd.
School/Discipline
Dissertation Note
Provenance
Description
Mini Review
Access Status
Rights
© 2004 Taylor & Francis Ltd