Risk factors for dogs becoming rectal carriers of multidrug-resistant Escherichia coli during hospitalization

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dc.contributor.authorGibson, J.
dc.contributor.authorMorton, J.
dc.contributor.authorCobbold, R.
dc.contributor.authorFilippich, L.
dc.contributor.authorTrott, D.
dc.date.issued2011
dc.description.abstractThis study aimed to identify risk factors for dogs becoming rectal carriers of multidrug-resistant (MDR) Escherichia coli while hospitalized in a veterinary teaching hospital. Exposures to potential risk factors, including treatments, hospitalization, and interventions during a 42-day pre-admission period and hospitalization variables, were assessed for 90 cases and 93 controls in a retrospective, risk-based, case-control study. On multivariable analyses, hospitalization for >6 days [odds ratio (OR) 2.91–8.00], treatment with cephalosporins prior to admission (OR 5.04, 95% CI 1.25–20.27), treatment with cephalosporins for >1 day (OR 5.18, 95% CI 1.86–14.41), and treatment with metronidazole (OR 7.17, 95% CI 1.01–50.79) while hospitalized were associated with increased risk of rectal carriage of MDR E. coli during hospitalization. The majority of rectal isolates obtained during the study period conformed to MDR E. coli clonal groups previously obtained from extraintestinal infections. These results can assist the development of improved infection control guidelines for the management of dogs in veterinary hospitals to prevent the occurrence of nosocomial clinical infections.
dc.description.statementofresponsibilityJ. S. Gibson, J. M.Morton, R. N. Cobbold, L. J. Filippich and D. J. Trott
dc.identifier.citationEpidemiology and Infection, 2011; 139(10):1511-1521
dc.identifier.doi10.1017/S0950268810002785
dc.identifier.issn0950-2688
dc.identifier.issn1469-4409
dc.identifier.orcidTrott, D. [0000-0002-8297-5770]
dc.identifier.urihttp://hdl.handle.net/2440/65892
dc.language.isoen
dc.publisherCambridge Univ Press
dc.rightsCopyright © Cambridge University Press 2010
dc.source.urihttps://doi.org/10.1017/s0950268810002785
dc.subjectDomestic pets
dc.subjectE. coli
dc.subjectepidemiology
dc.subjectnosocomial.
dc.titleRisk factors for dogs becoming rectal carriers of multidrug-resistant Escherichia coli during hospitalization
dc.typeJournal article
pubs.publication-statusPublished

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