Protein adsorption on low temperature alpha alumina films for surgical instruments
Date
2008
Authors
Cloud, A.
Kumar, S.
Kavdia, M.
Abu Safe, H.
Gordon, M.
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Journal article
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Surface and Coatings Technology, 2008; 203(5-7):913-917
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Abstract
Bulk alumina has been shown to exhibit reduced protein adsorption, a property that can be exploited for developing alumina-coated surgical instruments and devices. Alpha alumina thin films were deposited on surgical stainless steel substrates to investigate the adsorption of a model protein (BSA, bovine serum albumin). The films were deposited at 480 ??C by AC inverted cylindrical magnetron sputtering. Films were obtained at 6 kW and 50% oxygen partial pressure by volume. The presence of alpha-phase alumina has been shown by transmission electron microscopy. Results indicate that there was a 50% reduction in protein adsorption for samples with the alumina coating compared to those with no coating.
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Copyright 2008 Elsevier