An evaluation of effect of pterygopalatine fossa injection with local anesthetic and adrenalin in the control of nasal bleeding during endoscopic sinus surgery

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dc.contributor.authorWormald, P.
dc.contributor.authorAthanasiadis, T.
dc.contributor.authorRees, G.
dc.contributor.authorRobinson, S.
dc.date.issued2005
dc.description.abstractBackground: The aim of this study was to determine the effect of pterygopalatine fossa infiltration with lidocaine and adrenalin on bleeding in the surgical field during endoscopic sinus surgery. Methods: A prospective blind randomized controlled trial was performed. Fifty-five patients were randomized to receive a unilateral transoral infiltration of the pterygopalatine fossa with 2 mL of 2% lidocaine and 1:80,000 adrenalin. The operating surgeon was blinded as to which side had been infiltrated at the start of surgery. The surgical field was graded on a previously validated surgical field grading scale every 15 minutes with the side being operated on alternated every 30 minutes. The pulse, mean arterial blood pressure, and endtidal CO2 concentration were monitored with each surgical field observation. Results: At each individual time point from 30 minutes to 3.5 hours there was a significant difference in surgical grade between injected and noninjected sides in favor of the injected side (p = 0.01). The difference between surgical grades averaged across all time points was slight but significant. The injected side had an overall mean of 2.59 (SE, 0.22) compared with 2.99 (SE, 0.23) for the noninjected side. Heart rate also was found to correlate independently to surgical grade. Conclusion: Injection of the pterygopalatine fossa resulted in an improved surgical field during endoscopic sinus surgery.
dc.description.statementofresponsibilityWormald, Peter-John; Athanasiadis, Theodore; Rees, Guy and Robinson, Simon
dc.identifier.citationAmerican Journal of Rhinology and Allergy, 2005; 19(3):288-292
dc.identifier.doi10.1177/194589240501900313
dc.identifier.issn1945-8924
dc.identifier.issn1050-6586
dc.identifier.orcidWormald, P. [0000-0001-7753-7277]
dc.identifier.urihttp://hdl.handle.net/2440/16654
dc.language.isoen
dc.publisherOcean Side Publications Inc
dc.source.urihttps://doi.org/10.1177/194589240501900313
dc.subjectNasal Mucosa
dc.subjectParanasal Sinuses
dc.subjectHumans
dc.subjectEpistaxis
dc.subjectSinusitis
dc.subjectNasal Polyps
dc.subjectChronic Disease
dc.subjectBlood Loss, Surgical
dc.subjectEpinephrine
dc.subjectLidocaine
dc.subjectAnesthetics, Local
dc.subjectVasoconstrictor Agents
dc.subjectEndoscopy
dc.subjectTreatment Outcome
dc.subjectPerioperative Care
dc.subjectProspective Studies
dc.subjectDouble-Blind Method
dc.subjectAdult
dc.subjectAged
dc.subjectMiddle Aged
dc.subjectFemale
dc.subjectMale
dc.titleAn evaluation of effect of pterygopalatine fossa injection with local anesthetic and adrenalin in the control of nasal bleeding during endoscopic sinus surgery
dc.typeJournal article
pubs.publication-statusPublished

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