Synthesis of the putative structure of tridachiahydropyrone

dc.contributor.authorJeffery, D.
dc.contributor.authorPerkins, M.
dc.contributor.authorWhite, J.
dc.date.issued2005
dc.description.abstract[reaction: see text] A short total synthesis of the putative structure of the marine natural product tridachiahydropyrone as a single enantiomer is described. Novel steps include a cuprate addition and cyclization to form a cyclohexanone ring and formation of the bicyclic pyrone with P(2)O(5) on Celite. The spectroscopic data obtained for compound 1 do not match those reported for tridachiahydropyrone; therefore, revision of the assigned natural product structure is warranted.
dc.description.statementofresponsibilityDavid W. Jeffery, Michael V. Perkins, and Jonathan M. White
dc.identifier.citationOrganic Letters, 2005; 7(8):1581-1584
dc.identifier.doi10.1021/ol050236d
dc.identifier.issn1523-7060
dc.identifier.issn1523-7052
dc.identifier.orcidJeffery, D. [0000-0002-7054-0374]
dc.identifier.urihttp://hdl.handle.net/2440/66396
dc.language.isoen
dc.publisherAmer Chemical Soc
dc.rightsCopyright © 2005 American Chemical Society
dc.source.urihttps://doi.org/10.1021/ol050236d
dc.subjectAnimals
dc.subjectMollusca
dc.subjectPyrones
dc.subjectNuclear Magnetic Resonance, Biomolecular
dc.subjectMolecular Structure
dc.subjectCyclization
dc.subjectStereoisomerism
dc.titleSynthesis of the putative structure of tridachiahydropyrone
dc.typeJournal article
pubs.publication-statusPublished

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