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Older persons' use of antidepressants in long-term care facilities : closing the quality use of medicines gap /

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dc.contributor.authorHughes, Georgina
dc.contributor.schoolUniversity of South Australia. UniSA Clinical and Health Sciences.
dc.contributor.schoolUniSA Clinical and Health Sciences
dc.date.issued2025
dc.description1 ethesis (xxi, 304 pages) :
dc.descriptionillustrations (some colour), charts (chiefly colour).
dc.descriptionIncludes bibliographical references (pages 209-243)
dc.description.abstractDespite concerns about the potentially inappropriate use of psychotropic medicines in long-term care facilities (LTCFs), antidepressant use has not been the focus of national activities to improve quality use of medicines in Australian LTCFs. This thesis comprises a series of pharmacoepidemiological analyses using routinely collected, de-identified data from a national aged and health care data platform. These studies determined: (i) national trends in antidepressant use in LTCFs, (ii) transitions of care before LTCF entry, (iii) care setting and factors associated with antidepressant initiation, (iv) duration of antidepressant use after LTCF entry, and (v) risk of adverse outcomes associated with mirtazapine versus sertraline use in LTCFs. This work informs clinical practice and policy developments that are required to achieve quality use of medicines in LTCFs.
dc.description.dissertationThesis (PhD(Pharmaceutical Science))--University of South Australia, 2025.
dc.identifier.urihttps://hdl.handle.net/11541.2/43236
dc.language.isoen
dc.provenanceCopyright 2025 Georgina Anne Hughes.
dc.subjectantidepressant;long-term care;Australia
dc.subject.lcshAntidepressive agents
dc.subject.lcshGeriatric pharmacology.
dc.subject.lcshLong-term care facilities
dc.titleOlder persons' use of antidepressants in long-term care facilities : closing the quality use of medicines gap /
dc.typethesis
dcterms.accessRights506 0#$fstar $2Unrestricted online access
ror.fileinfo12302722750001831 13302722740001831 Hughes, Georgina - Thesis
ror.mmsid9916977716401831

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