Use of a matrix scaffold for tissue engineering and bone regeneration
Date
2003
Authors
Bartold, P.
Xiao, Y.
Editors
Ellingsen, J.
Lyngstadaas, S.
Lyngstadaas, S.
Advisors
Journal Title
Journal ISSN
Volume Title
Type:
Book chapter
Citation
Bio-implant interface - improving biomaterials and tissue reactions, 2003 / Ellingsen, J., Lyngstadaas, S. (ed./s), pp.247-259
Statement of Responsibility
P. Mark Bartold and Yin Xiao
Conference Name
Abstract
The regeneration of bone defects resulting from tumors, diseases, infections, trauma, biochemical disorders, and abnormal skeletal development poses a significant clinical challenge. Over the years, many bone graft substitutes including autografts, allografts, and synthetic materials have been developed. The relative shortage and traumatic harvesting procedures required for autografts, together with the potential for disease transmission and adverse host immune reactions against allografts, have increased the need to develop synthetic bone substitutes.