Mediation of circadian rhythms

Date

2002

Authors

Kennaway, D.

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Patent

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David Kennaway

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Abstract

Method for mediating the effects of light on melatonin rhythmicity in mammals and a method of mediating circadian rhythms, effected by the administration of a compound or compounds effective at a 5-HT2c serotonin receptor site. By administration of selected doses of the 5-HT2c receptor active compound it is possible to advance or delay circadian rhythms as measured by the rate of melatonin production or moderation of core body temperature rhythms.

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United States Patent 6403651

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