An integrated genomics approach to improving wool productivity and quality
Date
2009
Authors
Hynd, P.
Bawden, C.
Rufaut, N.
Norris, B.
McDowall, M.
Nixon, A.
Yu, Z.
Pearson, A.
Nattrass, G.
Gordon-Thompson, C.
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Advisors
Journal Title
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Type:
Conference paper
Citation
Proceedings of the eighteenth conference : Matching genetics and environment : a new look at an old topic, Barossa Valley, S.A., 28th September - 1st October 2009 / Association for the Advancement of Animal Breeding and Genetics: pp.312-321
Statement of Responsibility
P. I. Hynd, C. S. Bawden, N. W. Rufaut, B. J. Norris, M. McDowall, A. J. Nixon, Z. Yu, A. J. Pearson, G. S. Nattrass, C. Gordon-Thompson, G. P. Moore, S. M. Dunn, N. M. Edwards, D. Smith and C. J. McLaughlan
Conference Name
Association for the Advancement of Animal Breeding and Genetics Conference (18th : 2009 : Barossa Valley, South Australia)
Abstract
This paper summarises the approach taken in a national research program designed to "identify and utilise genes of importance in the sheep industries". The sheepgenomics program as it was known, comprised meat, wool and parasite subprograms with an underpinning core technology subprogram. The wool subprogram used a combination of gene association and functional biology studies to identify genes and gene networks amenable to manipulation or selection to improve wool production and quality. Significant progress was made in identifying genes involved in wool follicle initiation, hair cycle regulation, recessive black pigmentation and fleece rot. Manipulation of key windows of foetal development resulted in lifetime positive changes in wool production, an important proof of concept in functional, developmental genomics.
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© Association for the Advancement of Animal Breeding and Genetics, 2009