Boron toxicity tolerance in barley arising from efflux transporter amplification

Date

2007

Authors

Sutton, T.
Baumann, U.
Hayes, J.
Collins, N.
Shi, B.
Schnurbusch, T.
Hay, A.
Mayo, G.
Pallotta, M.
Tester, M.

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Science, 2007; 318(5855):1446-1449

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Tim Sutton, Ute Baumann, Julie Hayes, Nicholas C. Collins, Bu-Jun Shi, Thorsten Schnurbusch, Alison Hay, Gwenda Mayo, Margaret Pallotta, Mark Tester and Peter Langridge

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Abstract

Both limiting and toxic soil concentrations of the essential micronutrient boron represent major limitations to crop production worldwide. We identified Bot1, a BOR1 ortholog, as the gene responsible for the superior boron-toxicity tolerance of the Algerian barley landrace Sahara 3771 (Sahara). Bot1 was located at the tolerance locus by high-resolution mapping. Compared to intolerant genotypes, Sahara contains about four times as many Bot1 gene copies, produces substantially more Bot1 transcript, and encodes a Bot1 protein with a higher capacity to provide tolerance in yeast. Bot1 transcript levels identified in barley tissues are consistent with a role in limiting the net entry of boron into the root and in the disposal of boron from leaves via hydathode guttation.

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