A cost-effectiveness analysis of heroin detoxification methods in the Australian National Evaluation of Pharmacotherapies for Opioid Dependence (NEPOD)

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dc.contributor.authorShanahan, M.
dc.contributor.authorDoran, C.
dc.contributor.authorDigiusto, E.
dc.contributor.authorBell, J.
dc.contributor.authorLintzeris, N.
dc.contributor.authorWhite, J.
dc.contributor.authorAli, R.
dc.contributor.authorSaunders, J.
dc.contributor.authorMattick, R.
dc.contributor.authorGilmour, S.
dc.date.issued2006
dc.description.abstractAbstract This economic evaluation was part of the Australian National Evaluation of Pharmacotherapies for Opioid Dependence (NEPOD) project. Data from four trials of heroin detoxification methods, involving 365 participants, were pooled to enable a comprehensive comparison of the cost-effectiveness of five inpatient and outpatient detoxification methods. This study took the perspective of the treatment provider in assessing resource use and costs. Two short-term outcome measures were used—achievement of an initial 7-day period of abstinence, and entry into ongoing post-detoxification treatment. The mean costs of the various detoxification methods ranged widely, from AUD $491 (buprenorphine-based outpatient); to AUD $605 for conventional outpatient; AUD $1404 for conventional inpatient; AUD $1990 for rapid detoxification under sedation; and to AUD $2689 for anaesthesia per episode. An incremental cost-effectiveness analysis was carried out using conventional outpatient detoxification as the base comparator. The buprenorphine-based outpatient detoxification method was found to be the most cost-effective method overall, and rapid opioid detoxification under sedation was the most cost-effective inpatient method
dc.description.statementofresponsibilityM.D. Shanahan, C.M. Doran, E. Digiusto, J. Bell, N. Lintzeris, J. White, R. Ali, J.B. Saunders, R.P. Mattick and S. Gilmour
dc.description.urihttp://www.elsevier.com/wps/find/journaldescription.cws_home/471/description#description
dc.identifier.citationAddictive Behaviors, 2006; 31(3):371-387
dc.identifier.doi10.1016/j.addbeh.2005.05.016
dc.identifier.issn0306-4603
dc.identifier.issn1873-6327
dc.identifier.orcidAli, R. [0000-0003-2905-8153]
dc.identifier.urihttp://hdl.handle.net/2440/22769
dc.language.isoen
dc.publisherPergamon-Elsevier Science Ltd
dc.source.urihttps://doi.org/10.1016/j.addbeh.2005.05.016
dc.subjectHeroin
dc.subjectdetoxification
dc.subjectcost-effectiveness analysis
dc.subjectNEPOD
dc.subjectBuprenorphine
dc.subjectNaltrexone
dc.titleA cost-effectiveness analysis of heroin detoxification methods in the Australian National Evaluation of Pharmacotherapies for Opioid Dependence (NEPOD)
dc.typeJournal article
pubs.publication-statusPublished

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