Processing and characterization of elastomeric polycaprolactone triol-citrate coatings for biomedical applications

Date

2014

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Safizadeh Shirazi, H.
Forooshani, P.K.
Pingguan Murphy, B.
Djordjevic, I.

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Journal article

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Progress in Organic Coatings, 2014; 77(4):821-829

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Abstract

In this paper we describe the synthesis, processing and characterization of a novel elastic polyester coating created by carrying out catalyst-free polyesterification between biocompatible and non-toxic multifunctional reactants, namely polycaprolactone triol and citric acid. The physico-chemical and surface properties of the resulting polyester coatings and films have been investigated. This new material has been characterized by matrix-assisted laser desorption time-of-flight mass spectrometry (MALDI-ToF-MS), nuclear magnetic resonance spectroscopy (NMR), Fourier-transform infra-red spectroscopy (FTIR), water-in-air contact angle measurements, scanning electron microscopy (SEM), thermal analysis (DSC), mechanical tests and swelling experiments. The polymer structure, surface properties (morphology and chemistry), mechanical integrity and hydration of the elastomer can be controlled by simple variation of the initial citric acid concentration in the polymer formation. This feature of the novel polyester material presents a significant development in the production of advanced coatings for biomedical applications.

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Copyright 2014 Elsevier

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