Deterministic and stochastic modelling of endosome escape by Staphylococcus aureus: "quorum" sensing by a single bacterium

Date

2005

Authors

Koerber, A.
King, J.
Williams, P.

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Journal article

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Journal of Mathematical Biology, 2005; 50(4):440-488

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A.J. Koerber, J.R. King and P. Williams

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Abstract

Deterministic and stochastic models describing quorum sensing by Staphylococcus aureus within an endosome, and the subsequent escape via the production of virulence factors, are developed and analysed. Particular attention is given to a biologically-relevant asymptotic limit of the problem, for which the solutions, including the endosome escape time, can be explicitly characterised in terms of the model parameters.

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The original publication can be found at www.springerlink.com

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