A Convenient Method for the Synthesis of Dehydroquinic Acid
Date
2003
Authors
Le Sann, C.
Abell, C.
Abell, A.
Editors
Advisors
Journal Title
Journal ISSN
Volume Title
Type:
Journal article
Citation
Synthetic Communications: an international journal for rapid communication of synthetic organic chemistry, 2003; 33(4):527-533
Statement of Responsibility
Christine Le Sann; Chris Abell; Andrew D. Abell
Conference Name
Abstract
A convenient synthesis of dehydroquinic acid and its corresponding methyl ester are described. Protection of the trans diol of quinic acid, followed by PCC oxidation, gave fully protected dehydroquinic acid. This gave methyl dehydroquinate on mild acid catalyzed hydrolysis. Ester hydrolysis then gave potassium dehydroquinate which was treated with amberlite to afford dehydroquinic acid.