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Corneal aberrations measured with a high-resolution Scheimpflug tomographer: repeatability and reproducibility

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dc.contributor.authorMcAlinden, C.
dc.contributor.authorSchwiegerling, J.
dc.contributor.authorKhadka, J.
dc.contributor.authorPesudovs, K.
dc.date.issued2020
dc.description.abstractPURPOSE: To evaluate the precision of elevation and wavefront aberration measurements with the Pentacam HR (Oculus Optikgeräte GmbH). SETTING: Flinders University, Australia. DESIGN: Instrument evaluation study. METHODS: A randomly selected eye of 100 participants was scanned twice with the Pentacam HR by 1 observer on the 3 measurement modes: 25-picture, 50-picture, and cornea fine. A second observer performed 2 scans on the same random eye with the 25-picture mode. Repeatability and reproducibility were assessed using the within-subject SD (Sw) statistic from a 1-way analysis of variance. RESULTS: From the 100 scanned eyes, the higher-order aberration root mean square (RMS) repeatability limit for both elevation and wavefront, and anterior and posterior measurements was 0.03 μm for all 3 measurement modes. Anterior, posterior, and total corneal wavefront Zernike terms were highly precise, with most Zernike terms displaying a repeatability limit of 0.03 μm. The least repeatable measurement was the posterior elevation Zernike term with the 25-picture scan (repeatability limit 1.50 μm). The cornea fine measurement mode provided the most precise measurements. Reproducibility limits (second observer) were similar to repeatability limits with the 25-picture scan mode. CONCLUSIONS: The Pentacam HR provided highly precise aberration outputs. The most precise measurements are achievable with the cornea fine measurement mode and wavefront aberrations. One should be cognizant of posterior elevation aberration precision, particularly for lower radial order and higher azimuthal frequency terms. Accounting for tilt and misalignment of aberrations, all RMS and Zernike aberrations were extremely precise (repeatability and reproducibility limit less than 0.000001 μm).
dc.identifier.citationJournal of Cataract and Refractive Surgery, 2020; 46(4):581-590
dc.identifier.doi10.1097/j.jcrs.0000000000000084
dc.identifier.issn1873-4502
dc.identifier.issn1873-4502
dc.identifier.urihttps://hdl.handle.net/11541.2/142432
dc.language.isoen
dc.publisherLippincott Williams & Wilkins
dc.rightsCopyright 2020 Published by Wolters Kluwer on behalf of ASCRS and ESCRSPublished by Wolters Kluwer Health
dc.source.urihttps://doi.org/10.1097/j.jcrs.0000000000000084
dc.titleCorneal aberrations measured with a high-resolution Scheimpflug tomographer: repeatability and reproducibility
dc.typeJournal article
pubs.publication-statusPublished
ror.fileinfo12197267040001831 13197277220001831 Corneal_aberrations_measured_with_a.14.pdf
ror.mmsid9916399808301831

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