A meta-analysis of sperm donation offspring health outcomes

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dc.contributor.authorAdams, D.
dc.contributor.authorClark, R.
dc.contributor.authorDavies, M.
dc.contributor.authorDe Lacey, S.
dc.date.issued2017
dc.description.abstractAlthough the use of donor sperm as a treatment modality for male infertility has become common place, the health outcomes for those conceived has been poorly studied. A structured search of the literature using PubMed, EMBASE and Cochrane Reviews was performed to investigate the health outcomes of offspring conceived from donor sperm. Eight studies were eligible and included in the review, and of these, three were included in a meta-analysis. Meta-analysis of clinical outcomes showed that donor sperm neonates are not at increased risk of being born of low birth weight (<2500 g), preterm (<37 weeks) or with increased incidences of birth defects, than spontaneously conceived neonates.
dc.identifier.citationJournal of Developmental Origins of Health and Disease, 2017; 8(1):44-55
dc.identifier.doi10.1017/S2040174416000489
dc.identifier.issn2040-1744
dc.identifier.issn2040-1752
dc.identifier.orcidDavies, M. [0000-0002-5809-7541] [0000-0003-1526-0801]
dc.identifier.urihttp://hdl.handle.net/2440/112564
dc.language.isoen
dc.publisherCAMBRIDGE UNIV PRESS
dc.source.urihttp://www.ncbi.nlm.nih.gov/pubmed/27573256
dc.subjectDonor conception
dc.subjectmeta-analysis
dc.subjectneonate
dc.subjectoutcome
dc.subjectsperm
dc.titleA meta-analysis of sperm donation offspring health outcomes
dc.typeJournal article
pubs.publication-statusPublished

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