Apo2L/TRAIL in breast cancer bone metastasis: in vitro and in vivo studies into molecular mechanisms of action and resistance.

dc.contributor.author	Thai, Le Minh	en
dc.contributor.school	School of Medicine : Orthopaedics and Trauma	en
dc.date.issued	2007	en
dc.description.abstract	This thesis describes two studies, one in vitro and one in vivo, which show that Apo2L/TRAIL can prevent breast cancer-induced bone destruction, and highlight the potential of this ligand for the treatment of metastatic breast cancer in bone. They also highlight the complexity of Apo2L/TRAIL signalling, and the need for further studies into this area to fully exploit the potential of Apo2L/TRAIL as an anti-cancer agent for breast and other cancers.	en
dc.description.dissertation	Thesis (Ph.D.) -- University of Adelaide, School of Medicine, 2007	en
dc.identifier.uri	http://hdl.handle.net/2440/57334
dc.provenance	This electronic version is made publicly available by the University of Adelaide in accordance with its open access policy for student theses. Copyright in this thesis remains with the author. This thesis may incorporate third party material which has been used by the author pursuant to Fair Dealing exceptions. If you are the owner of any included third party copyright material you wish to be removed from this electronic version, please complete the take down form located at: http://www.adelaide.edu.au/legals
dc.subject	breast cancer; metastasis	en
dc.title	Apo2L/TRAIL in breast cancer bone metastasis: in vitro and in vivo studies into molecular mechanisms of action and resistance.	en
dc.type	Thesis	en

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