Perinatal management of trisomy 18: a survey of obstetricians in Australia, New Zealand and the UK

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dc.contributor.authorWilkinson, D.
dc.contributor.authorde Crespigny, L.
dc.contributor.authorLees, C.
dc.contributor.authorSavulescu, J.
dc.contributor.authorThiele, P.
dc.contributor.authorTran, T.
dc.contributor.authorWatkins, A.
dc.date.issued2014
dc.description.abstractOBJECTIVE The objective of this study was to explore the attitudes of obstetricians in Australia, New Zealand and the UK towards prenatally diagnosed trisomy 18 (T18). METHOD Obstetricians were contacted by email and invited to participate in an anonymous electronic survey. RESULTS Survey responses were obtained from 1018/3717 (27%) practicing obstetricians/gynaecologists. Most (60%) had managed a case of T18 in the last 2 years. Eighty-five per cent believed that T18 was a ‘lethal malformation’, although 38% expected at least half of liveborn infants to survive for more than 1 week. Twenty-one per cent indicated that a vegetative existence was the best developmental outcome for surviving children. In a case of antenatally diagnosed T18, 95% of obstetricians would provide a mother with the option of termination. If requested, 99% would provide maternal-focused obstetric care (aimed at maternal wellbeing rather than fetal survival), whereas 80% would provide fetal-oriented obstetric care (to maximise fetal survival). Twenty-eight per cent would never discuss the option of caesarean; 21% would always discuss this option. Management options, attitudes and knowledge of T18 were associated with location, practice type, gender and religion of obstetricians. CONCLUSION There is variability in obstetricians' attitudes towards T18, with significant implications for management of affected pregnancies.
dc.description.statementofresponsibilityD. J. C. Wilkinson, L. de Crespigny, C. Lees, J. Savulescu, P. Thiele, T. Tran and A. Watkins
dc.identifier.citationPrenatal Diagnosis, 2014; 34(1):42-49
dc.identifier.doi10.1002/pd.4249
dc.identifier.issn0197-3851
dc.identifier.issn1097-0223
dc.identifier.urihttp://hdl.handle.net/2440/85166
dc.language.isoen
dc.publisherJohn Wiley & Sons
dc.rights© 2013 The Authors. Prenatal Diagnosis published by John Wiley & Sons, Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
dc.source.urihttps://doi.org/10.1002/pd.4249
dc.subjectChromosomes, Human, Pair 18
dc.subjectHumans
dc.subjectTrisomy
dc.subjectPrenatal Diagnosis
dc.subjectPerinatal Care
dc.subjectAbortion, Induced
dc.subjectAttitude of Health Personnel
dc.subjectObstetrics
dc.subjectSex Factors
dc.subjectPregnancy
dc.subjectReligion
dc.subjectPhysicians
dc.subjectAustralia
dc.subjectNew Zealand
dc.subjectFemale
dc.subjectMale
dc.subjectCongenital Abnormalities
dc.subjectSurveys and Questionnaires
dc.subjectPractice Patterns, Physicians'
dc.subjectUnited Kingdom
dc.subjectTrisomy 18 Syndrome
dc.titlePerinatal management of trisomy 18: a survey of obstetricians in Australia, New Zealand and the UK
dc.typeJournal article
pubs.publication-statusPublished

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