Immunogenicity and safety of measles-mumps-rubella and varicella vaccines coadministered with a fourth dose of Haemophilus influenzae type b and Neisseria meningitidis serogroups C and Y-tetanus toxoid conjugate vaccine in toddlers: a pooled analysis of randomized trials

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dc.contributor.authorBryant, K.
dc.contributor.authorMcVernon, J.
dc.contributor.authorMarchant, C.
dc.contributor.authorNolan, T.
dc.contributor.authorMarshall, G.
dc.contributor.authorRichmond, P.
dc.contributor.authorMarshall, H.
dc.contributor.authorNissen, M.
dc.contributor.authorLambert, S.
dc.contributor.authorAris, E.
dc.contributor.authorMesaros, N.
dc.contributor.authorMiller, J.
dc.date.issued2012
dc.description.abstractA pooled analysis was conducted of 1,257 toddlers who received a fourth dose of Haemophilus influenzae type b-Neisseria meningitidis serogroups C and Y-tetanus toxoid conjugate vaccine (HibMenCY-TT ) or Hib conjugate vaccine (Hib polysaccharide conjugated to N. meningitidis outer membrane protein) coadministered with measles-mumps-rubella (MMR) and varicella (VAR) vaccines (NCT00134719/NCT00289783). Noninferiority of immunological responses to MMR and VAR was demonstrated between groups and incidences of MMR- and VAR-specific solicited symptoms were similar, indicating that HibMenCY-TT can be coadministered with MMR and VAR.
dc.description.statementofresponsibilityKristina A. Bryant, Jodie McVernon, Colin D. Marchant, Terry Nolan, Gary S. Marshall, Peter Richmond, Helen Marshall, Michael Nissen, Stephen B. Lambert, Emmanuel Aris, Narcisa Mesaros and Jacqueline M. Miller
dc.identifier.citationHuman Vaccines and Immunotherapeutics, 2012; 8(8):1036-1041
dc.identifier.doi10.4161/hv.20357
dc.identifier.issn2164-554X
dc.identifier.issn2164-554X
dc.identifier.orcidMarshall, H. [0000-0003-2521-5166]
dc.identifier.urihttp://hdl.handle.net/2440/73562
dc.language.isoen
dc.publisherLandes Bioscience
dc.rights© 2012 Landes Bioscience
dc.source.urihttps://doi.org/10.4161/hv.20357
dc.subjectHaemophilus influenzae tybe b
dc.subjectNeisseria meningitidis scrogroups C and Y
dc.subjectMMR
dc.subjectvaricella
dc.subjectvaccination
dc.subjecttoddlers
dc.titleImmunogenicity and safety of measles-mumps-rubella and varicella vaccines coadministered with a fourth dose of Haemophilus influenzae type b and Neisseria meningitidis serogroups C and Y-tetanus toxoid conjugate vaccine in toddlers: a pooled analysis of randomized trials
dc.typeJournal article
pubs.publication-statusPublished

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