Mechanistic insights into the formation of polyion complex aggregates from cationic thermoresponsive diblock copolymers

Date

2021

Authors

Read, E.
Lonetti, B.
Gineste, S.
Sutton, A.T.
Di Cola, E.
Castignolles, P.
Gaborieau, M.
Mingotaud, A.F.
Destarac, M.
Marty, J.D.

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Journal of Colloid and Interface Science, 2021; 590:268-276

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Abstract

Hypothesis: The formation of polyion complexes (PICs) comprising thermoresponsive polymers is intended to result in the formation of aggregates that undergo significant structural changes with temperature. Moreover the observed modifications might be critically affected by polymer structure and PICs composition. Experiments: Different block copolymers based on cationic poly(3-acrylamidopropyltrimethylammonium chloride) and thermoresponsive poly(N-isopropylacrylamide) were synthesized by aqueous RAFT/MADIX polymerization at room temperature. Addition of poly(acrylic acid) in a controlled fashion led to the formation of PICs aggregates. The structural changes induced by temperature were characterized by differential scanning calorimetry, Nuclear Magnetic Resonance spectroscopy and scattering methods. Findings: Thermoresponsive PICs undergo significant structural changes when increasing temperature above the cloud point of the thermoresponsive block. The reversibility of these phenomena depends strongly on the structural parameters of the block copolymers and on PICs composition.

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Data source: Supplementary data

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Copyright 2021 Elsevier

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