Use of cidofovir in polymavirus BK viral nephropathy in two renal allograft recipients
Date
2003
Authors
Lim, W.
Mathew, T.
Cooper, J.
Bowden, S.
Russ, G.
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Journal article
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Nephrology, 2003; 8(6):318-323
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Wai H Lim, Timothy H Mathew, John E Cooper, Scott Bowden and Graeme R Russ
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Abstract
Polyomavirus BK viral allograft nephropathy is a potentially reversible cause of deteriorating function of kidney allografts. Initial treatment involves reducing immunosuppressive medications, with low-dose cidofovir an effective alternative in refractory cases. We describe two cases of BK viral allograft nephropathy responding to low-dose cidofovir after a reduction in immunosuppressive medications failed to clear the virus or stabilize the deterioration in renal function. There were no significant side-effects from this treatment in either patient.
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Copyright © John Wiley & Sons, Inc. All Rights Reserved.