Neonatal morbidity after induction vs expectant monitoring in intrauterine growth restriction at term: a subanalysis of the DIGITAT RCT

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dc.contributor.authorBoers, K.
dc.contributor.authorvan Wyk, L.
dc.contributor.authorvan der Post, J.
dc.contributor.authorKwee, A.
dc.contributor.authorvan Pampus, M.
dc.contributor.authorSpaanderman, M.
dc.contributor.authorDuvekot, J.
dc.contributor.authorBremer, H.
dc.contributor.authorDelemarre, F.
dc.contributor.authorBloemenkamp, K.
dc.contributor.authorde Groot, C.
dc.contributor.authorWillekes, C.
dc.contributor.authorRijken, M.
dc.contributor.authorRoumen, F.
dc.contributor.authorThornton, J.
dc.contributor.authorvan Lith, J.
dc.contributor.authorMol, B.
dc.contributor.authorle Cessie, S.
dc.contributor.authorScherjon, S.
dc.date.issued2012
dc.description.abstractObjective The Disproportionate Intrauterine Growth Intervention Trial at Term (DIGITAT) compared induction of labor and expectant management in suspected intrauterine growth restriction (IUGR) at term. In this subanalysis, we report neonatal morbidity between the policies based on the Morbidity Assessment Index for Newborns (MAIN). Study Design We used data from the DIGITAT. For each neonate, we calculated the MAIN score, a validated outcome scale. Results There were no differences in mean MAIN scores or in MAIN morbidity categories. We found that neonatal admissions are lower after 38 weeks' gestational age compared with 36 and 37 weeks in both groups. Conclusion The incidence of neonatal morbidity in IUGR at term is comparable and relatively mild either after induction or after an expectant policy. However, neonatal admissions are lower after 38 weeks of pregnancy, so if induction to preempt possible stillbirth is considered, it is reasonable to delay until 38 weeks, provided watchful monitoring.
dc.description.statementofresponsibilityKim E. Boers, Linda van Wyk, Joris A. M. van der Post, Anneke Kwee, Maria G. van Pampus, Marc E. A. Spaanderdam, Johannes J. Duvekot, Henk A. Bremer, Friso M. C. Delemarre, Kitty W. M. Bloemenkamp, Christianne J.M. de Groot, Christine Willekes, Monique Rijken, Frans J.M.E. Roumen, Jim G. Thornton, Jan M.M. van Lith, Ben W.J. Mol, Saskia le Cessie, Sicco A. Scherjon, for the DIGITAT Study Group
dc.identifier.citationAmerican Journal of Obstetrics and Gynecology, 2012; 206(4):344.e1-344.e7
dc.identifier.doi10.1016/j.ajog.2012.01.015
dc.identifier.issn0002-9378
dc.identifier.issn1097-6868
dc.identifier.orcidMol, B. [0000-0001-6887-0262] [0000-0001-8337-550X]
dc.identifier.urihttp://hdl.handle.net/2440/88160
dc.language.isoen
dc.publisherElsevier
dc.rightsCopyright © 2012 Mosby, Inc.
dc.source.urihttps://doi.org/10.1016/j.ajog.2012.01.015
dc.subjectDisproportionate Intrauterine Growth Intervention Trial at Term; induction of labor; intrauterine growth restriction at term; Morbidity Assessment Index for Newborns score; neonatal morbidity
dc.titleNeonatal morbidity after induction vs expectant monitoring in intrauterine growth restriction at term: a subanalysis of the DIGITAT RCT
dc.typeJournal article
pubs.publication-statusPublished

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