Design of Stimuli-Responsive Peptides and Proteins

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dc.contributor.authorLi, Y.
dc.contributor.authorYang, G.
dc.contributor.authorGerstweiler, L.
dc.contributor.authorThang, S.H.H.
dc.contributor.authorZhao, C.-X.
dc.date.issued2023
dc.descriptionPublished online: December 7, 2022
dc.description.abstractStimuli-responsive peptides and proteins are an exciting class of smart biomaterials for various applications and have received significant attention over the past decades. A wide variety of stimuli such as temperature, pH, ions, enzymes, magnetic field, redox, etc., are explored. This article provides a review of five intensively studied types of stimuli-responsive peptides and proteins, their design principles and applications, including temperature-, pH-, light-, metal ion-, and enzyme-responsive with an emphasis on the key design concepts and switch function. Moreover, typical examples of their applications are discussed to provide a better understanding of the design concept and underlying methodology. This review will facilitate and inspire future innovation toward new peptide- and protein-based materials and their diverse applications.
dc.description.statementofresponsibilityYang Li, Guangze Yang, Lukas Gerstweiler, San H. Thang, and Chun-Xia Zhao
dc.identifier.citationAdvanced Functional Materials, 2023; 33(7):2210387-1-2210387-31
dc.identifier.doi10.1002/adfm.202210387
dc.identifier.issn1616-301X
dc.identifier.issn1616-3028
dc.identifier.orcidYang, G. [0000-0002-6194-1918]
dc.identifier.orcidGerstweiler, L. [0000-0002-2421-5503]
dc.identifier.urihttps://hdl.handle.net/2440/137266
dc.language.isoen
dc.publisherWiley-VCH GmbH
dc.relation.granthttp://purl.org/au-research/grants/arc/CE200100009
dc.relation.granthttp://purl.org/au-research/grants/nhmrc/2008698
dc.rights© 2022 The Authors. Advanced Functional Materials published by Wiley-VCH GmbH. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
dc.source.urihttps://doi.org/10.1002/adfm.202210387
dc.subjectlight; metal ions; peptides; pH; proteins; stimuli-responsive behavior; temperature
dc.titleDesign of Stimuli-Responsive Peptides and Proteins
dc.typeJournal article
pubs.publication-statusPublished

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