Multimorbidity, polypharmacy and the identification of patients at high risk of adverse medicine events /
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(Published version)
Date
2020
Authors
Masnoon, Nashwa
Editors
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Type:
thesis
Citation
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Abstract
This project aimed to identify older patients with multimorbidity who may be at risk of poor health outcomes due to potentially inappropriate polypharmacy. Systematic reviews of polypharmacy definitions and tools demonstrated that definitions focus on the number of medicines and tools do not combine important factors such as drug-drug and drug-disease interactions. A survey of clinical experts showed that factors such as high-risk medicines and drug-drug interactions are considered when assessing polypharmacy. Factors important for polypharmacy assessment identified from the literature and survey, were tested against the outcomes of hospitalisation and mortality in an older multimorbid population. A combination of demographics, medicines count, specific drugs such as sedatives and anticholinergics, and diseases such as heart failure were important for identifying high-risk patients.
School/Discipline
University of South Australia. School of Pharmacy and Medical Sciences.
School of Pharmacy and Medical Sciences.
School of Pharmacy and Medical Sciences.
Dissertation Note
Thesis (PhD(Pharmacy and Medical Science))--University of South Australia, 2020.
Provenance
Copyright 2020 Nashwa Masnoon.
Description
1 ethesis (xviii, 227, 10, 21, 9, 10, 9 pages) :
illustrations (colour), charts (some colour)
Includes bibliographical references (pages 172-193)
illustrations (colour), charts (some colour)
Includes bibliographical references (pages 172-193)
Access Status
506 0#$fstar $2Unrestricted online access