Biological treatment of ranitidine and cefixime trihydrate mixed solution by activated sludge in sequencing batch reactor

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2021

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Aber, S.
Ghalamchi, L.
Hosseinzadeh, H.
Nofouzi, K.
Naseri, A.

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Desalination and Water Treatment, 2021; 225:94-103

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Abstract

Hospital wastewater consists of various pharmaceutical compounds. If a proper treatment procedure is not considered, discharging these compounds into the environment can cause serious problems in the aqueous ecosystem, as well as those connected to humans wellbeing. This study aimed to remove ranitidine and cefixime trihydrate drugs simultaneously using adapted activated sludge in a sequencing batch reactor (SBR) and to monitor each drug degradation separately by means of statistical analysis using MATLAB 8.1 software. Total nitrogen, total phosphorus, and chemical oxygen demand analyses were conducted; furthermore, the spectrophotometric spectrum of the solution was recorded as well. The partial least squares analytical method using MATLAB 8.1 software was utilized to analyze the results with the obtained R2 value of 0.99 for both ranitidine and cefixime. 71.67% of ranitidine and 59.67% of cefixime trihydrate were removed during the biological treatment in the SBR.

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Copyright 2021 Desalination Publications

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